Description / human Flt-3 Ligand protein
Flt3-ligand (flk2-ligand) stimulates the proliferation and colony formation of certain BM precursor cells including CD34+ cells. Flt3-ligand produced in E. coli is a soluble non-glycosylated 17.6 kDa polypeptide containing 155 amino acid residues which comprises the extracellular domain of the transmembrane flt3-ligand protein.
More Information
| Size | 50 µg |
|---|---|
| Source | E. coli |
| Biological Activity | Determined by the dose-dependent stimulation of the proliferation of human AML5 cells. The expected ED50 for this effect is 0,5 – 1ng/ml. |
| Purity Confirmation | > 98% by SDS-PAGE & Coomassie stain |
| Length [aa] | 155 |
| Molecular Weight | 17.6 kDa |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Protein Sequence | TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTA |
| Synonyms | FLT3; FLK2; STK1; CD135; FLK-2 |
| Uniprot ID | P49771 |
| Protein RefSeq | NP_001450.2 |
| mRNA RefSeq | NM_001459.3 |