human NT-4 protein Human 10 µg

In stock

Cat-Nr.
100-087
Size
10 µg
  €221.00

Description / human NT-4 protein

NT-4 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues).

More Information

Size 10 µg
Source E. coli
Biological Activity Determined by its ability to bind recombinant human TrkB Fc Chimera in a functional ELISA.
Purity Confirmation > 98% by SDS-PAGE & HPLC analyses
Length [aa] 130
Molecular Weight 14 kDa
Species Reactivity Rat, Frog, Human, Mouse
Formulation lyophilized
Protein Sequence GVSETAPASR RGELAVCDAV SGWVTDRRTA VDLRGREVEV LGEVPAAGGS PLRQYFFETR CKADNAEEGG PGAGGGGCRG VDRRHWVSEC KAKQSYVRAL TADAQGRVGW RWIRIDTACV CTLLSRTGRA
Synonyms NTF4; NT4; NT5; NT-4; NT-5; NTF5; GLC10; GLC1O; NT-4/5
Uniprot ID P34130
Protein RefSeq NP_006170.1
mRNA RefSeq NM_006179.4

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