Description / anti-human NT-4 monoclonal antibody
NT-4 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues).
More Information
| Size | 500 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG1 |
| Species Reactivity | Human |
| Formulation | lyophilized from PBS |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
| Preparation | Produced in BALB/c x c57BL/6 F1 mice using recombinant human NT-4 as the immunizing antigen. IgG2a antibody was purified from ascites fluid on a Protein A affinity column. |
| Antigen | Recombinant Human NT-4 |
| Application | ELISA |
| Synonyms | NTF4; NT4; NT5; NT-4; NT-5; NTF5; GLC10; GLC1O; NT-4/5 |
| Uniprot ID | P34130 |
| Protein RefSeq | NP_006170.1 |
| mRNA RefSeq | NM_006179.4 |