Description / mouse KC (CXCL1) protein
All three isoforms of GRO or KC are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant murine KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.
More Information
| Size | 20 µg |
|---|---|
| Source | E. coli |
| Biological Activity | Determined by its ability to chemoattract total human neutrophil population using a concentration range of 10.0-100.0 ng/ml. |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 72 |
| Molecular Weight | 7.8 kDa |
| Species Reactivity | Human, Rat, Mouse |
| Formulation | lyophilized |
| Protein Sequence | APIANELRCQ CLQTMAGIHL KNIQSLKVLP SGPHCTQTEV IATLKNGREA CLDPEAPLVQ KIVQKMLKGV PK |
| Synonyms | CXCL1 |
| Uniprot ID | P12850 |
| Protein RefSeq | NP_032202.1 |
| mRNA RefSeq | NM_008176.3 |