Description / anti-mouse KC (CXCL1) polyclonal antibody
The predicted amino acid sequence of the mouse KC gene product indicates KC is a member of the CXC subfamily of chemokines. The protein sequence of mouse KC shows approximately 63% identity to that of mouse MIP-2. In addition, the protein sequence of KC is approximately 60% identical to the human GROs. It has been suggested that mouse KC and MIP-2 are the homologs of the human GROs and rat CINCs. KC mRNA is expressed in macrophages, endothelial cells, and fibroblasts. The rat chemokines CINC (cytokine-induced neutrophil chemoattractant)-1, CINC-2 alpha, CINC-2 beta and CINC-3 constitute a group of rat CXC chemokines that show significant sequence similarity to human GROs and mouse MIP-2 and KC.
More Information
| Size | 100 µg |
|---|---|
| Source | Rabbit |
| Clone Nr. | Rabbit IgG |
| Species Reactivity | Mouse |
| Formulation | lyophilized from PBS |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
| Preparation | Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant murine KC. Anti-murine KC specific antibody was purified by affinity chromatography employing immobilized murine KC matrix. |
| Antigen | Recombinant mouse KC (CXCL1) |
| Application | ELISA, WB |
| Synonyms | CXCL1 |
| Uniprot ID | P12850 |
| Protein RefSeq | NP_032202.1 |
| mRNA RefSeq | NM_008176.3 |