Follistatin Human 20 µg

In stock

Cat-Nr.
100-172
Size
20 µg
  €221.00

Description / Follistatin

Follistatin belongs to a group of structurally-diverse diffusible proteins that binds to TGF-beta ligands and inhibit their activity by hindering access to signaling receptors. This naturally occurring antagonist binds to Activin, BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin is a 31.5 kDa protein containing 288 amino acids including 36 cysteine residues.

More Information

Size 20 µg
Source E. coli
Biological Activity Determined by its ability to neutralize Activin A inhibitory effect of murine MPC-11 cells. The expected ED50 is 0.1-0.4 µg/ml in the presence of 7.5 ng/ml Activin A.
Purity Confirmation > 95% by SDS-PAGE & HPLC analyses
Length [aa] 288
Molecular Weight 31.5 kDa
Species Reactivity Chicken, Mouse, Human, Rat
Formulation lyophilized
Protein Sequence GNCWLRQAKN GRCQVLYKTE LSKEECCSTG RLSTSWTEED VNDNTLFKWM IFNGGAPNCI PCKETCENVD CGPGKKCRMN KKNKPRCVCA PDCSNITWKG PVCGLDGKTY RNECALLKAR CKEQPELEVQ YQGRCKKTCR DVFCPGSSTC VVDQTNNAYC VTCNRICPEP ASSEQYLCGN DGVTYSSACH LRKATCLLGR SIGLAYEGKC IKAKSCEDIQ CTGGKKCLWD FK
Synonyms FST; FS
Uniprot ID P19883
Protein RefSeq NP_006341.1
mRNA RefSeq NM_006350

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