Follistatin Anti-Human 100 µg

In stock

Cat-Nr.
102-P227
Size
100 µg
  €271.00

Description / Follistatin

Follistatin is a secreted protein that binds to ligands of the TGF-β family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-β ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-β1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Human Follistatin is aa 31-33 kDa protein containing 288 amino acids. Its primary structure contains three cysteine-rich domains (called FS domains), each followed by a protease-inhibitory kazal domain.

More Information

Size 100 µg
Source Rabbit
Clone Nr. Rabbit IgG
Species Reactivity Human
Formulation lyophilized from PBS
Buffer PBS
Reconstitution Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Stability and Storage The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
Preparation Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant Follistatin. Anti-Human Follistatin specific antibody was purified by affinity chromatography employing immobilized Follistatin matrix.
Antigen Recombinant human Follistatin
Application ELISA, WB
Synonyms FST; FS
Uniprot ID P19883
Protein RefSeq NP_006341.1
mRNA RefSeq NM_006350

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