Description / human FGF-5 protein
FGF-5 is a secreted heparin binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-5 binds to FGFR 1c and 2c, and plays a regulatory role in the hair growth cycle. Recombinant human FGF-5 is a 27.6 kDa protein consisting of 252 amino acid residues.
More Information
| Size | 500 µg |
|---|---|
| Source | E. coli |
| Biological Activity | The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg. |
| Purity Confirmation | > 95% by SDS-PAGE & HPLC analyses |
| Length [aa] | 252 |
| Molecular Weight | 27.6 kDa |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | 5 mM Tris, pH 7.2 + 50 mM NaCl |
| Protein Sequence | MAWAHGEKRL APKGQPGPAA TDRNPIGSSS RQSSSSAMSS SSASSSPAAS LGSQGSGLEQ SSFQWSPSGR RTGSLYCRVG IGFHLQIYPD GKVNGSHEAN MLSVLEIFAV SQGIVGIRGV FSNKFLAMSK KGKLHASAKF TDDCKFRERF QENSYNTYAS AIHRTEKTGR EWYVALNKRG KAKRGCSPRV KPQHISTHFL PRFKQSEQPE LSFTVTVPEK KNPPSPIKSK IP |
| Synonyms | FGF5; HBGF-5; Smag-82 |
| Uniprot ID | P12034 |
| Protein RefSeq | NP_004455 |
| mRNA RefSeq | NM_004464 |