FGF-5 Anti-Human 500 µg

In stock

Cat-Nr.
101-M71
Size
500 µg
  €221.00

Description / FGF-5

The FGF family is comprised of at least seven polypeptides that are potent regulators of cell proliferation, differentiation and function. All FGFs have two conserved cysteine residues and share 30-50% sequence homology at the amino acid level. FGF5 was originally identified as a transforming gene by the NIH3T3 focus formation assay using DNA derived from human tumors. FGF5 cDNA encodes a 267 amino acid residue protein with a putative 22 amino acid residue signal peptide. The murine homologue of FGF5 was cloned and found to be 84% homologous to the human protein at the amino acid sequence level. Human and murine FGF5 exhibit cross species activity. In vitro, recombinant human FGF5 is a mitogen for Balb/3T3 fibroblasts and bovine heart endothelial cells. FGF5 was also reported to be a major muscle-derived survival factor for cultured spinal moto-neurons.

More Information

Size 500 µg
Source Mouse
Isotype IgG1
Species Reactivity Human
Formulation lyophilized from PBS
Buffer PBS
Reconstitution Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Stability and Storage The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
Preparation Produced in BALB/c mice using recombinant human FGF-5 as the immunizing antigen. This IgG1/K antibody was purified from a Protein A chromatography column.
Antigen Recombinant human FGF-5
Application ELISA, N
Synonyms FGF5; HBGF-5; Smag-82
Uniprot ID P12034
Protein RefSeq NP_004455
mRNA RefSeq NM_004464

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