Description / FGF-5
FGF-5 is a secreted heparin binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-5 binds to FGFR 1c and 2c, and plays a regulatory role in the hair growth cycle. Recombinant human FGF-5 is a 27.6 kDa protein consisting of 252 amino acid residues.
More Information
Size | 50 µg |
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Source | E. coli |
Biological Activity | The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg. |
Purity Confirmation | > 95% by SDS-PAGE & HPLC analyses |
Length [aa] | 252 |
Molecular Weight | 27.6 kDa |
Species Reactivity | Human |
Formulation | lyophilized |
Buffer | 5 mM Tris, pH 7.2 + 50 mM NaCl |
Protein Sequence | MAWAHGEKRL APKGQPGPAA TDRNPIGSSS RQSSSSAMSS SSASSSPAAS LGSQGSGLEQ SSFQWSPSGR RTGSLYCRVG IGFHLQIYPD GKVNGSHEAN MLSVLEIFAV SQGIVGIRGV FSNKFLAMSK KGKLHASAKF TDDCKFRERF QENSYNTYAS AIHRTEKTGR EWYVALNKRG KAKRGCSPRV KPQHISTHFL PRFKQSEQPE LSFTVTVPEK KNPPSPIKSK IP |
Synonyms | FGF5; HBGF-5; Smag-82 |
Uniprot ID | P12034 |
Protein RefSeq | NP_004455 |
mRNA RefSeq | NM_004464 |