Eotaxin-2 (CCL24) Human 20 µg

In stock

Cat-Nr.
100-013
Size
20 µg
  €221.00

Description / Eotaxin-2 (CCL24)

Eotaxin-2 is a CC chemokine that signals through the CCR3 receptor. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemo attracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multi potential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 a.a. residues for the murine homolog, without C-terminal truncation). Recombinant human Eotaxin-2 is an 8.8 kDa protein containing 78 amino acid residues.

More Information

Size 20 µg
Source E. coli
Biological Activity Determined by its ability to chemoattract using human peripheral blood eosinophils using a concentration of 50-100 ng/ml.
Purity Confirmation > 98% by SDS-PAGE & HPLC analyses
Length [aa] 78
Molecular Weight 8.8 kDa
Species Reactivity Mouse, Human, Bacteria
Formulation lyophilized
Protein Sequence VVIPSPCCMF FVSKRIPENR VVSYQLSSRS TCLKGGVIFT TKKGQQFCGD PKQEWVQRYM KNLDAKQKKA SPRARAVA
Synonyms CCL24; Ckb-6; MPIF2; MPIF-2; SCYA24
Uniprot ID O00175
Protein RefSeq NP_002982.2
mRNA RefSeq NM_002991

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