Description / anti-human TNFSF3 (Lymphotoxin beta) monoclonal antibody
Lymphotoxin-alpha (LT alpha) and Lymphotoxin-beta (LT beta) are members of the TNF superfamily designated TNFSF1 and TNFSF3, respectively. LT alpha is a soluble protein while LT beta is a type II transmembrane protein. Secreted LT alpha will assemble as a homotrimer, LT alpha 3, or as a complex with membrane-associated LT beta to generate two types of heterotrimers, LT alpha 1/beta 2 and LT alpha 2/beta 1. Lymphotoxins are expressed by activated CD4+ T cells, unpolarized IL-2-secreting effector T cells, and Th1 effector cells.
More Information
| Size | 100 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG2 |
| Clone Nr. | (#3J26) |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of TNFSF3 (also called lymphotoxin-b). |
| Antigen | Recombinant human TNFSF3 |
| Application | WB |
| Synonyms | LTB; p33; TNFC; TNFSF3 |
| Uniprot ID | Q06643 |
| Protein RefSeq | NP_002332.1 |
| mRNA RefSeq | NM_002341.1 |