Description / anti-human TNFSF11 (TRANCE) monoclonal antibody
TNF-related activation-induced cytokines (TRANCE), also called RANK Ligand (RANKL, receptor activator of NF-kB ligand), osteoprotegerin ligand (OPGL), and osteoclast differentiation factor (ODF), is a member of the TNF superfamily. Mouse and human TRANCE share 85% amino acid sequence identity. TRANCE is primarily expressed in T cells and T cell rich organs, such as thymus and lymph nodes.
More Information
| Size | 50 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG3 |
| Clone Nr. | (#5F12) |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human TNFSF11 recombinant protein (also called TRANCE). |
| Antigen | human recombinant TNFSF11 |
| Application | WB |
| Synonyms | TNFSF11; ODF; OPGL; sOdf; CD254; OPTB2; RANKL; TRANCE; hRANKL2 |
| Uniprot ID | O14788 |
| Protein RefSeq | NP_003692.1 |
| mRNA RefSeq | NM_003701.3 |