Description / anti-human TNFRSF8 monoclonal antibody
CD30/TNFRSF8 is a type I transmembrane glycoprotein belonging to the TNF receptor superfamily. The ligand for CD30 is CD30 Ligand/TNFSF8 (CD153), a member of the TNF superfamily. CD30 ligation by CD30 Ligand mediates pleiotropic effects, including cell proliferation, activation, differentiation and apoptosis.
More Information
| Size | 100 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG2 |
| Clone Nr. | (#5K28) |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of TNFSF8 (also called CD30) extracellular domain. |
| Antigen | recombinant human TNFRSF8 EC domain |
| Application | WB, FC, Stimulation |
| Synonyms | TNFRSF8; CD30; Ki-1; D1S166E |
| Uniprot ID | P28908 |
| Protein RefSeq | NP_001234.2 |
| mRNA RefSeq | NM_001243.3 |