Description / anti-human TNFRSF3 monoclonal antibody
Lymphotoxin beta receptor (LT beta R), also known as TNF C receptor and TNF R2rp, was originally identified as a transcribed sequence with homology to the TNF receptor superfamily. The cytoplasmic region of LT beta R shares little sequence similarity with other TNF receptor family members, suggesting that different signaling mechanisms may be utilized. LT beta R is expressed in a variety of tissues including visceral and lymphoid tissues. The human and mouse LT beta R share 76% amino acid sequence identity.
More Information
| Size | 100 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG1 |
| Clone Nr. | (#3T24) |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of TNFRSR3 extracellular domain (also called Lymphotoxin b R). |
| Antigen | recombinant human TNFRSF3 EC domain |
| Application | WB, FC |
| Synonyms | LTBR; CD18; TNFCR; D12S370; TNFR-RP; TNFRSF3; TNFR2-RP; LT-BETA-R; TNF-R-III |
| Uniprot ID | P36941 |
| Protein RefSeq | NP_002333.1 |
| mRNA RefSeq | NM_002342 |