Description / anti-human TNFRSF18 (GITR) monoclonal antibody
GITR (glucocorticoid-induced tumor necrosis factor receptor), also named AITR (activation-inducible TNFreceptor superfamily member) and TNFRSF18, is a 228amino acid typeI transmembrane protein belonging to the TNFreceptor superfamily. The GITR cytoplasmic domain has striking similarity to the cytoplasmic domain of 4-1BB and CD27.
More Information
| Size | 50 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG1 |
| Clone Nr. | (#7R12) |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of TNFRSF18 extracellular domain (also called GITR). |
| Antigen | recombinant human TNFRSF18 EC domain |
| Application | WB, FC, N |
| Synonyms | TNFRSF18; AITR; GITR; CD357; GITR-D |
| Uniprot ID | Q9Y5U5 |
| Protein RefSeq | NP_004186.1 |
| mRNA RefSeq | NM_004195.2 |