Description / rat SDF-1 beta (CXCL12) protein
SDF-1α and β are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor. Recombinant rat SDF-1β is an 8.4 kDa protein containing 72 amino acid residues.
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| Size | 10 µg |
|---|---|
| Source | E. coli |
| Biological Activity | Determined by its ability to chemoattract human monocytes using a concentration range of 100.0-200.0 ng/ml. |
| Purity Confirmation | > 95% by SDS-PAGE & HPLC analyses |
| Length [aa] | 72 |
| Molecular Weight | 8.4 kDa |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Protein Sequence | KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNKRL KM |
| Synonyms | Cxcl12; Sdf1 |
| Uniprot ID | Q9QZD1 |
| Protein RefSeq | NP_071513.1 |
| mRNA RefSeq | NM_022177.3 |