Description / rat SDF-1 alpha (CXCL12) protein
Stromal cell-derived factor (SDF)-1 alpha and SDF-1 beta are the first cytokines initially identified using the signal sequence trap cloning strategy from a mouse bone-marrow stromal cell line. They are encoded by a single gene, PBSF, and arise by alternative splicing. The two proteins are identical except for the four amino acid residues that are present in the carboxy-terminus of SDF-1 beta and absent from SDF-1 alpha. SDF-1/PBSF is highly conserved between species. Human mature SDF-1 shares approximately 99% amino acid sequence identity with the mouse protein.
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| Size | 10 µg |
|---|---|
| Source | E. coli |
| Biological Activity | Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 50.0-100.0 ng/ml. |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 68 |
| Molecular Weight | 7.9 kDa |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Protein Sequence | KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNK |
| Synonyms | Cxcl12; Sdf1 |
| Uniprot ID | Q9QZD1 |
| Protein RefSeq | NP_071513.1 |
| mRNA RefSeq | NM_022177.3 |