Description / human Prolactin, pegylated protein
Prolactin, also known as mammotrophin, luterotropic hormone, and lutetropin, is a neuroendocrine hormone secreted by the pituitary gland. Its primary function is to promote and maintain lactation during pregnancy and suckling. In addition, Prolactin plays an immune-regulatory role by stimulating the activities of ornithine decarboxylase and protein kinase C, which are important for the proliferation, differentiation, and function of lymphocytes. Recombinant human Prolactin is a 23 kDa globular protein containing 200 amino acid residues.
More Information
| Size | 100 µg |
|---|---|
| Source | E. coli |
| Biological Activity | Determined by its ability to induce the proliferation of rat Nb2-11 cells in the concentration range of 0.1-1.0 ng/ml. |
| Purity Confirmation | > 99% by SDS-PAGE & HPLC analyses |
| Length [aa] | 200 |
| Molecular Weight | 23 kDa |
| Species Reactivity | Rat, Human |
| Formulation | lyophilized |
| Protein Sequence | MLPICPGGAA RCQVTLRDLF DRAVVLSHYI HNLSSEMFSE FDKRYTHGRG FITKAINSCH TSSLATPEDK EQAQQMNQKD FLSLIVSILR SWNEPLYHLV TEVRGMQEAP EAILSKAVEI EEQTKRLLEG MELIVSQVHP ETKENEIYPV WSGLPSLQMA DEESRLSAYY NLLHCLRRDS HKIDNYLKLL KCRIIHNNNC |
| Reconstitution | It is recommended to reconstitute the lyophilized pegylated hPRL in sterile water or 0.4% NaHCO3 adjusted tp pH 8-9, not less than 100µg/ml, which can then be further diluted to other aqueous solutions, preferably in presence of carrier protein. |
| Synonyms | Mammotropin, Luterotropic hormone, Lutetropin |
| Uniprot ID | P01236 |
| Protein RefSeq | NP_000939.1 |
| mRNA RefSeq | NM_000948 |