Description / human NT-3 (Animal Free) protein
NT-3 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous system, and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant Human NT-3 is a noncovalently linked homodimer of two 13.6 kDa polypeptide monomers (240 total amino acid residues).
More Information
| Size | 10 µg |
|---|---|
| Source | E. coli |
| Biological Activity | Determined by its ability to bind recombinant human TrkB Fc Chimera in a functional ELISA. |
| Purity Confirmation | ≥ 98% by SDS-PAGE gel and HPLC analyses. |
| Species Reactivity | Human, Mouse, Rat |
| Formulation | lyophilized |
| Synonyms | NTF3; NT3; HDNF; NGF2; NGF-2 |
| Uniprot ID | P20783 |
| Protein RefSeq | NP_001096124.1 |
| mRNA RefSeq | NM_001102654 |