Description / anti-human NKp80 monoclonal antibody
NKp80, also known as killer cell lectin-like receptor subfamily F, member 1 (KLRF1), is a type II transmembrane protein with a C-type lectin domain in its extracellular region. NKp80 is expressed at the cell surface of virtually all NK cells as a dimer of approximately 80 kDa. It has been shown to function as a co-receptor with natural cytotoxicity receptors (NCR) to induce activation of NK cell-mediated cytolysis.
More Information
| Size | 100 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG2 |
| Clone Nr. | (#7D32) |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with extracellular domain of human recombinant protein of NKp80, also called killer cell lectin-like receptor subfamily F, member 1 (KLRF1). |
| Antigen | recombinant human NKp80 |
| Application | FC |
| Synonyms | KLRF1; NKp80; CLEC5C |
| Uniprot ID | Q9NZS2 |
| Protein RefSeq | NP_057607.1 |
| mRNA RefSeq | NM_016523.1 |