Description / mouse MIP-3 beta (CCL19) protein
MIP-3β is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3β is active on murine cells. Mouse urine MIP-3β is a 9.2 kDa protein containing 83 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
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| Size | 20 µg |
|---|---|
| Source | E. coli |
| Biological Activity | Determined by its ability to chemoattract human mature dendritic cells using a concentration range of 10.0-100.0 ng/ml. |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 83 |
| Molecular Weight | 9.2 kDa |
| Species Reactivity | Human, Mouse, Monkey, Leech, Rat |
| Formulation | lyophilized |
| Protein Sequence | GANDAEDCCL SVTQRPIPGN IVKAFRYLLN EDGCRVPAVV FTTLRGYQLC APPDQPWVDR IIRRLKKSSA KNKGNSTRRS PVS |
| Synonyms | Ccl19; ELC; CKb11; MIP3B; Scya19; exodus-3 |
| Uniprot ID | O70460 |
| Protein RefSeq | NP_036018.1 |
| mRNA RefSeq | NM_011888 |