Description / human MIP-3 beta (CCL19) protein
MIP-3β is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3β is active on murine cells. Recombinant human MIP-3β is an 8.8 kDa protein containing 77 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
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| Size | 20 µg |
|---|---|
| Source | E. coli |
| Biological Activity | Determined by its ability to chemoattract human T cells using a concentration of 10.0-50.0 ng/ml. |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 77 |
| Molecular Weight | 8.8 kDa |
| Species Reactivity | Monkey, Mouse, Human, Leech, Bacteria |
| Formulation | lyophilized |
| Protein Sequence | GTNDAEDCCL SVTQKPIPGY IVRNFHYLLI KDGCRVPAVV FTTLRGRQLC APPDQPWVER IIQRLQRTSA KMKRRSS |
| Synonyms | CCL19; ELC; CKb11; MIP3B; MIP-3b; SCYA19 |
| Uniprot ID | Q99731 |
| Protein RefSeq | NP_006265 |
| mRNA RefSeq | NM_006274 |