Description / anti-human MIP-3 alpha monoclonal antibody
MIP-3α is a CC chemokine that is expressed in the liver, lymph nodes, appendix, PBL and lung and can signal through the CCR6 receptor. MIP-3α is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors. Human MIP-3α is an 8.0 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
More Information
| Size | 500 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG1, kappa |
| Species Reactivity | Human |
| Formulation | lyophilized from PBS |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
| Preparation | Produced from a hybridoma using purified recombinant, E. coli derived, human MIP-3 alpha. This IgG1k antibody was purified on a Protein G affinity column. |
| Antigen | Recombinant mouse MIP-3 alpha |
| Application | ELISA, WB |
| Synonyms | CCL20; CKb4; LARC; ST38; MIP3A; MIP-3a; SCYA20 |
| Uniprot ID | P78556 |
| Protein RefSeq | NP_004582.1 |
| mRNA RefSeq | NM_004591 |