Description / human MIA-2 (Melanoma inhibitory activity 2) protein
MIA2 is a secreted cytokine and a member of the MIA/OTOR family. Members of this family which also includes MIA, OTOR, and TANGO share a Src homology-3 (SH3)-like domain. MIA2 is predominantly expressed in hepatocytes. Elevated levels of MIA2 may represent a clinically useful marker for diagnosis of hepatic disease activity and severity. Recombinant human MIA-2 is a 101 amino acid, 11.5 kDa protein comprising the MIA homologous N-terminal region of the full length MIA-2 protein.
More Information
| Size | 5 µg |
|---|---|
| Source | E. coli |
| Biological Activity | Data not available. |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 101 |
| Molecular Weight | 11.5 kDa |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Protein Sequence | MLESTKLLAD LKKCGDLECE ALINRVSAMR DYRGPDCRYL NFTKGEEISV YVKLAGERED LWAGSKGKEF GYFPRDAVQI EEVFISEEIQ MSTKESDFLC L |
| Synonyms | MIA2 |
| Uniprot ID | Q96PC5 |
| Protein RefSeq | NP_473365 |
| mRNA RefSeq | NM_054024 |