Description / mouse MCP-3 (CCL7) protein
The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross- reacts across species. Recombinant murine MCP-3 is an 8.5 kDa protein containing 74 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
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| Size | 2 µg |
|---|---|
| Source | E. coli |
| Biological Activity | Determined by its ability to chemoattract Balb/C mouse spleen MNCs using a concentration range of 10.0-100.0 ng/ml. |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 74 |
| Molecular Weight | 8.5 kDa |
| Species Reactivity | Mouse, Human |
| Formulation | lyophilized |
| Protein Sequence | QPDGPNASTC CYVKKQKIPK RNLKSYRRIT SSRCPWEAVI FKTKKGMEVC AEAHQKWVEE AIAYLDMKTP TPKP |
| Synonyms | Ccl7; fic; marc; mcp3; MCP-3; Scya7 |
| Uniprot ID | Q03366 |
| Protein RefSeq | NP_038682.1 |
| mRNA RefSeq | NM_013654.3 |