Description / human MCP-2 (CCL8) (Animal Free) protein
The MCP proteins are members of the CC chemokine family that signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross-reacts across species. Recombinant Human MCP-2 (CCL8) is an 8.9 kDa protein containing 76 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
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| Size | 2 µg |
|---|---|
| Source | E. coli |
| Biological Activity | Determined by its ability to chemoattract monocytic leukemia THP-1 cells. |
| Purity Confirmation | ≥ 98% by SDS-PAGE gel and HPLC analyses. |
| Length [aa] | 76 |
| Molecular Weight | 8.9 kDa |
| Species Reactivity | Hamster, Monkey, Mouse, Rat, Human |
| Formulation | lyophilized |
| Protein Sequence | QPDSVSIPIT CCFNVINRKI PIQRLESYTR ITNIQCPKEA VIFKTKRGKE VCADPKERWV RDSMKHLDQI FQNLKP |
| Synonyms | CCL8; HC14; MCP2; MCP-2; SCYA8; SCYA10 |
| Uniprot ID | P80075 |
| Protein RefSeq | NP_005614 |
| mRNA RefSeq | NM_005623 |