Description / mouse LIX/CXCL5 (93 aa) protein
LIX is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. LIX is a chemoattractant for neutrophils. The two naturally occurring variants of LIX; LIX 1-78 (GCP-2) and LIX 9-78 (GCP-2), contain 78 and 70 amino acid residues, respectively. LIX contains the four conserved cysteine residues present in CXC chemokines, and also contains the ‘ELR’ motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors. Recombinant murine LIX is a 9.8 kDa protein containing 93 amino acid residues.
More Information
| Size | 5 µg |
|---|---|
| Source | E. coli |
| Biological Activity | Determined by its ability to chemoattract human neutrophils using a concentration range of 10-100 ng/ml. |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 93 |
| Molecular Weight | 9.8 kDa |
| Species Reactivity | Human, Mouse |
| Formulation | lyophilized |
| Protein Sequence | APSSVIAATE LRCVCLTVTP KINPKLIANL EVIPAGPQCP TVEVIAKLKN QKEVCLDPEA PVIKKIIIQK ILGSDKKKAK RNALAVERTA SVQ |
| Synonyms | Cxcl5; LIX; GCP-2; Scyb5; Scyb6; ENA-78; AMCF-II |
| Uniprot ID | P50228 |
| Protein RefSeq | NP_033167.2 |
| mRNA RefSeq | NM_009141.2 |