Description / anti-human Lipocalin-2 monoclonal antibody
The Lipocalin family comprises a diverse group of mostly secreted soluble proteins that bind hydrophobic ligands and act as transporters, carrying small molecules to specific cells. Lipocalins are related by possessing an 8-stranded beta-barrel structure. Lipocalin-1, also named tear lipocalin (TL), von Ebners gland protein (VEG) and tear pre-albumin, binds a large number of hydrophobic molecules and exhibits cysteine proteinase inhibitor and endonuclear activities. Lipocalin-2, also known as neutrophil gelatinase-associated lipocalin (NGAL), is a component of granules in neutrophils from tissues that are normally exposed to microorganisms and is upregulated during inflammation. Lipocalin-2 can form homodimers and can heterodimerize with the neutrophil gelatinase MMP-9.
More Information
| Size | 50 µg |
|---|---|
| Source | Rat |
| Isotype | IgG2 |
| Biological Activity | WB: 1:500-1000; IHC(Paraffin): 1:20-100 |
| Clone Nr. | (#2G32) |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of Lipocalin-1 (also called NGAL). |
| Antigen | recombinant human Lipocalin-2 |
| Application | WB, IHC (P) |
| Synonyms | LCN2; 24p3; MSFI; NGAL |
| Uniprot ID | P80188 |
| Protein RefSeq | NP_005555.2 |
| mRNA RefSeq | NM_005564.3 |