Description / anti-mouse Leptin R monoclonal antibody
Leptin receptor (OBR), also named B219, is a type I cytokine receptor family protein with significant amino acid sequence identity with gp130, G-CSF receptor, and the LIF receptor. Multiple isoforms of human and mouse OBR, including a long form (OBRL) with a large cytoplasmic domain capable of signal-transduction, and several receptor isoforms with short cytoplasmic domains (OBRS) lacking signal-transducing capabilities, have been identified.
More Information
| Size | 100 µg |
|---|---|
| Source | Rat |
| Isotype | IgG2 |
| Clone Nr. | (#9C29) |
| Species Reactivity | Mouse |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant Leptin R extracellular domain. The IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chroma |
| Antigen | recombinant mouse Leptin R EC domain |
| Application | WB |
| Synonyms | Lepr; db; Obr; obl; Leprb; Modb1; LEPROT; OB-RGRP; diabetes; obese-like |
| Uniprot ID | P48356 |
| Protein RefSeq | NP_666258.2 |
| mRNA RefSeq | NM_146146.2 |