Description / human LD78-beta/CCL3L1 protein
LD78-beta is a CC chemokine that is closely related to MIP-1 alpha. It signals through the CCR5 receptor and the beta-chemokine receptor, D6. LD78-beta has been shown to exhibit potent activity in HIV suppression assays. Recombinant human LD78-beta is a 7.7 kDa protein containing 70 amino acid residues, including the four conserved cysteine residues present in CC chemokines.
More Information
| Size | 500 µg |
|---|---|
| Source | E. coli |
| Biological Activity | Determined by its ability to chemoattract mouse BaF3 cells expressing the CCR5 receptor using a concentration range of 5-25 ng/ml. |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 70 |
| Molecular Weight | 7.7 kDa |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Protein Sequence | APLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPSV IFLTKRGRQV CADPSEEWVQ KYVSDLELSA |
| Synonyms | CCL3L1 |
| Uniprot ID | P16619 |
| Protein RefSeq | NP_066286.1 |
| mRNA RefSeq | NM_021006.4 |