Description / mouse JE (MCP-1, CCL2) protein
The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species. Recombinant murine JE is a 13.8 kDa protein containing 125 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
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| Size | 10 µg |
|---|---|
| Source | E. coli |
| Biological Activity | Determined by its ability to chemoattract Balb/C mouse spleen MNCs using a concentration range of 1.0-20.0 ng/ml. |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 125 |
| Molecular Weight | 13.8 kDa |
| Species Reactivity | Human, Mouse, Rabbit, Monkey, Bacteria |
| Formulation | lyophilized |
| Protein Sequence | QPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEWV QTYIKNLDRN QMRSEPTTLF KTASALRSSA PLNVKLTRKS EANASTTFST TTSSTSVGVT SVTVN |
| Synonyms | Ccl2; JE; HC11; MCAF; MCP1; MCP-1; Scya2; Sigje; SMC-CF; AI323594 |
| Uniprot ID | P10148 |
| Protein RefSeq | NP_035463.1 |
| mRNA RefSeq | NM_011333.3 |