Description / rat IL-7 protein
IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive. Recombinant rat IL-7 is a 15.0 kDa protein containing 130 amino acid residues
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| Size | 2 µg |
|---|---|
| Source | E. coli |
| Biological Activity | The ED50 was determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells is < 2.0 ng/ml, corresponding to a specific activity of > 5 x 106 units/mg. |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 130 |
| Molecular Weight | 15 kDa |
| Species Reactivity | Mouse |
| Formulation | lyophilized |
| Protein Sequence | MDCHIKDKDG KAFGSVLMIS INQLDKMTGT DSDCPNNEPN FFKKHLCDDT KEAAFLNRAA RKLRQFLKMN ISEEFNDHLL RVSDGTQTLV NCTSKEEKTI KEQKKNDPCF LKRLLREIKT CWNKILKGSI |
| Synonyms | Il7 |
| Uniprot ID | Q91Y32 |
| Protein RefSeq | NP_037242.2 |
| mRNA RefSeq | NM_013110 |