Description / rat IL-5 protein
IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Recombinant rat IL-5 is a 26.0 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains.
More Information
| Size | 10 µg |
|---|---|
| Source | E. coli |
| Biological Activity | The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is < 0.5 ng/ml, corresponding to a specific activity of > 2 x 106 units/mg. |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 113 |
| Molecular Weight | 26 kDa |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Protein Sequence | MEIPMSTVVK ETLIQLSTHR ALLTSNETMR LPVPTHKNHQ LCIGEIFQGL DILKNQTVRG GTVEILFQNL SLIKKYIDGQ KEKCGEERRK TRHFLDYLQE FLGVMSTEWA MEV |
| Synonyms | Il5; Il-5 |
| Uniprot ID | Q9R2C9 |
| Protein RefSeq | NP_068606.1 |
| mRNA RefSeq | NM_021834.1 |