Description / anti-mouse IL-5 monoclonal antibody
Interleukin 5 (IL-5) is a T cell-derived factor that promotes the proliferation, differentiation and activation of eosinophils. In mice, IL-5 is also a growth and differentiation factor for B cells. Various names previously used to describe IL-5 include: Tcell replacing factor (TRF), B cell growth factor II (BCGFII), B cell differentiation factor µ (BCDF µ), eosinophil differentiation factor (EDF) and eosinophil colony-stimulating factor (Eo-CSF). Biologically active IL-5 is a disulfide-linked homodimer. Rat IL-5 is 94% and 70% identical to mouse and human IL-5, respectively.
More Information
| Size | 50 µg |
|---|---|
| Source | Rat |
| Isotype | IgG1 |
| Clone Nr. | (#3M58) |
| Species Reactivity | Mouse |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with mouse recombinant protein of IL-5. |
| Antigen | recombinant mouse protein of IL-5 |
| Application | FC, N |
| Synonyms | Il5; Il-5 |
| Uniprot ID | P04401 |
| Protein RefSeq | NP_034688.1 |
| mRNA RefSeq | NM_010558.1 |