Description / mouse IL-4 protein
Interleukin 4 (IL-4) is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. It was initially identified as a B cell differentiation factor (BCDF), as well as a B cell stimulatory factor (BSF1). IL-4 has since been shown to have multiple biological effects on hematopoietic and non-hematopoietic cells, including B and T cells, monocytes, macrophages, mast cells, myeloid and erythroid progenitors, fibroblasts, and endothelial cells. Rat, mouse and human IL-4 are species-specific in their activities.
More Information
| Size | 5 µg |
|---|---|
| Source | E. coli |
| Biological Activity | The ED50 was determined by the dose-dependent proliferation of murine HT-2 cells is < 2.0 ng/ml, corresponding to a specific activity of > 5 x 105 units/mg. |
| N Terminal Sequence | MHIHG |
| Purity Confirmation | > 98% by SDS-PAGE & Coomassie stain |
| Length [aa] | 120 |
| Molecular Weight | 13.5 kDa |
| Species Reactivity | Rat, Pig, Mouse, Human, Leech, Trout |
| Formulation | lyophilized |
| Protein Sequence | MHIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDY S |
| Synonyms | Il4; Il-4; BSF-1 |
| Uniprot ID | P07750 |
| Protein RefSeq | NP_067258 |
| mRNA RefSeq | NM_021283 |