Description / anti-mouse IL-21 receptor monoclonal antibody
IL-21 R, also called NILR (novel interleukin receptor) is a type I cytokine receptor with four conserved cysteine residues and an extracellular WSXWS motif. It is most closely related to IL-2 R beta and IL-9 R alpha. Mouse and human IL-21 R share 62% amino acid identity. IL-21 R is expressed on lymphoid tissues, peripheral B cells, and cell lines of T, B and natural killer cell lineage. IL-21 mediated signaling requires the common gamma chain in addition to IL-21 R.
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| Size | 100 µg |
|---|---|
| Source | Rat |
| Isotype | IgG1 |
| Clone Nr. | (#7F27) |
| Species Reactivity | Mouse |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant protein of IL-21R extracellular domain. The IgG1 fraction of the culture supernatant was purified by Protein A/G affini |
| Antigen | Mouse recombinant EC domain of IL-21 R |
| Application | WB |
| Synonyms | Il21r; NILR |
| Uniprot ID | Q9JHX3 |
| Protein RefSeq | NP_068687.1 |
| mRNA RefSeq | NM_021887.2 |