Description / rat IL-2 protein
IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant rat IL-2 is a 15.3 kDa protein containing 134 amino acid residues.
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| Size | 250 µg |
|---|---|
| Source | E. coli |
| Biological Activity | The ED50 as determined by the dose-dependent stimulation of the proliferation of murine CTLL-2 cells is < 0.4 ng/ml, corresponding to a specific activity of > 2.5 x 106 units/mg. |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 134 |
| Molecular Weight | 15.3 kDa |
| Species Reactivity | Mouse, Rat |
| Formulation | lyophilized |
| Protein Sequence | MAPTSSPAKE TQQHLEQLLL DLQVLLRGID NYKNLKLPMM LTFKFYLPKQ ATELKHLQCL ENELGALQRV LDLTQSKSFH LEDAGNFISN IRVTVVKLKG SENKFECQFD DEPATVVEFL RRWIAIAQSI ISTM |
| Synonyms | rbcL |
| Uniprot ID | P17108 |
| Protein RefSeq | NP_446288.1 |
| mRNA RefSeq | NM_053836.1 |