Description / mouse IL-2 protein
IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant murine IL-2 is a 17.2 kDa protein, containing 149 amino acid residues.
More Information
| Size | 20 µg |
|---|---|
| Source | E. coli |
| Biological Activity | The ED50 as determined by the dose dependent stimulation of murine CTLL-2 cells is < 0.2 ng/ml, corresponding to a specific activity of > 5 x 106 units/mg. |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 149 |
| Molecular Weight | 17.2 kDa |
| Species Reactivity | Human, Mouse, Leech |
| Formulation | lyophilized |
| Protein Sequence | PTSSSTSSST AEAQQQQQQQ QQQQQHLEQL LMDLQELLSR MENYRNLKLP RMLTFKFYLP KQATELKDLQ CLEDELGPLR HVLDLTQSKS FQLEDAENFI SNIRVTVVKL KGSDNTFECQ FDDESATVVD FLRRWIAFCQ SIISTSPQ |
| Synonyms | Il2; Il-2 |
| Uniprot ID | P04351 |
| Protein RefSeq | NP_032392.1 |
| mRNA RefSeq | NM_008366.3 |