Description / anti-human IL-2 monoclonal antibody
Interleukin 2 (IL-2) was initially identified as a T cell growth factor that is produced by T cells following activation by mitogens or antigens. Since then, it has also been shown to stimulate the growth and differentiation of B cells, natural killer (NK) cells, lymphocyte activated killer (LAK) cells, monocytes/macrophages and oligodendrocytes. At the amino acid sequence level, there is approximately 60% - 90% similarity between species. Mature human IL-2 shows 65%, 67%, 72%, 78%, and 64% aa identity to mouse, rat, pig, cat, and cow IL-2, respectively.
More Information
| Size | 500 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG1 |
| Species Reactivity | Human |
| Formulation | lyophilized from PBS |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
| Preparation | Produced in BALB/c mice using highly pure (>98%) recombinant human IL-2 as the immunizing antigen. This IgG1K antibody was purified from ascites fluid by Protein A affinity chromatography. |
| Antigen | recombinant human IL-2 |
| Application | ELISA |
| Synonyms | IL2; IL-2; TCGF; lymphokine |
| Uniprot ID | P60568 |
| Protein RefSeq | NP_000577 |
| mRNA RefSeq | NM_000586 |