anti-human IL-17A polyclonal antibody Anti-Human 100 µg
Description / anti-human IL-17A polyclonal antibody
The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimer. IL-17A exhibits cross-species bioactivity between human and murine cells.
More Information
| Size | 100 µg |
|---|---|
| Source | Goat |
| Clone Nr. | Goat IgG |
| Species Reactivity | Human |
| Formulation | lyophilized from PBS |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
| Preparation | Produced from sera of goats pre-immunized with highly pure (>98%) recombinant hIL-17A. Anti-hIL-17A specific antibody was purified by affinity chromatography employing immobilized hIL-17 matrix. |
| Antigen | Recombinant human IL-17A |
| Application | ELISA, WB |
| Synonyms | IL17A; IL17; CTLA8; IL-17; IL-17A |
| Uniprot ID | Q16552 |
| Protein RefSeq | NP_002181.1 |
| mRNA RefSeq | NM_002190.2 |