Description / anti-mouse IL-17 receptor monoclonal antibody
IL-17 binds to IL-17 receptors (IL-17 R), which share no homology with any known family of receptors. While the expression of IL-17 is restricted to activated T cells, IL-17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The amino acid sequence of human IL-17 R is 69% identical to mouse IL-17 R.
More Information
| Size | 100 µg |
|---|---|
| Source | Rat |
| Isotype | IgG2 |
| Clone Nr. | (#6C38) |
| Species Reactivity | Mouse |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant protein of IL-17R extracellular domain. The IgG2 fraction of the culture supernatant was purified by Protein A/G affini |
| Antigen | Mouse recombinant EC domain of IL-17R |
| Application | WB |
| Synonyms | Il17ra; Il17r; Cdw217; VDw217; AW538159 |
| Uniprot ID | Q60943 |
| Protein RefSeq | NP_032385.1 |
| mRNA RefSeq | NM_008359.2 |