Description / human IL-13 protein
Interleukin-13 is an immunoregulatory protein produced by immune effector cells such as activated T-lymphocytes, mast cells and NK cells. IL-13 reduces inflammation in monocytes and macrophages by inhibiting cytokines such as IL-1β, TNF-α, IL-6, and IL-8. Human and mouse IL-13 are cross-reactive. The biological activities of IL-13 include the stimulation of B cell proliferation and immunoglobulins production. Recombinant Human IL-13 is a 12.6 kDa protein containing 115 amino acid residues.
More Information
| Size | 100 µg |
|---|---|
| Source | E. coli |
| Biological Activity | The ED50 as determined by the dose-dependent proliferation of TF-1 cells was ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg. |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 115 |
| Molecular Weight | 12.6 kDa |
| Species Reactivity | Mouse, Human, Monkey, Pig, Leech |
| Formulation | lyophilized |
| Protein Sequence | MSPGPVPPST ALRELIEELV NITQNQKAPL CNGSMVWSIN LTAGMYCAAL ESLINVSGCS AIEKTQRMLS GFCPHKVSAG QFSSLHVRDT KIEVAQFVKD LLLHLKKLFR EGRFN |
| Synonyms | IL13; ALRH; BHR1; P600; IL-13 |
| Uniprot ID | P35225 |
| Protein RefSeq | NP_002179.2 |
| mRNA RefSeq | NM_002188 |