Description / anti-human IL-11 monoclonal antibody
Interleukin 11 (IL-11), also known as adipogenesis inhibitory factor (AGIF), has multiple effects on both hematopoietic and nonhematopoietic cells. Many of the biological effects described for IL-11 overlap those for IL-6. IL-11 exerts its biological activities through binding to a specific high-affinity receptor complex consisting of an IL-11 receptor chain and gp130.
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| Size | 500 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG2 |
| Biological Activity | Immunostaining: This antibody stained human brain stroke (including control cortex and stroke core areas) tissue. The primary antibody was incubated at 2.5 µg/ml overnight at 4°C. This was followed by a fluorophore conjugated secondary antibody. Neutraliz |
| Species Reactivity | Human |
| Formulation | lyophilized from PBS |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
| Preparation | Produced in BALB/c x C57BL/6F1, mice using recombinant human IL-11 as the immunizing antigen. IgG1 antibody was purified from ascites fluid on a Protein A affinity column. |
| Antigen | Recombinant mouse IL-11 |
| Application | ELISA, N, IHC |
| Synonyms | IL11; AGIF; IL-11 |
| Uniprot ID | P20809 |
| Protein RefSeq | NP_000632.1 |
| mRNA RefSeq | NM_000641 |