Description / anti-human IL-11 monoclonal antibody
Interleukin 11 (IL-11), also known as adipogenesis inhibitory factor (AGIF), has multiple effects on both hematopoietic and nonhematopoietic cells. Many of the biological effects described for IL-11 overlap those for IL-6. IL-11 exerts its biological activities through binding to a specific high-affinity receptor complex consisting of an IL-11 receptor chain and gp130.
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| Size | 500 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG1k |
| Biological Activity | In a sandwich ELISA (assuming 100μL/well), a concentration of 2.0-4.0 μg/mL of this antibody will detect Recombinant Human IL-11 when used with biotinylated antigen affinity purified Anti-Human IL-11 as the detection antibody. |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge the vial prior to opening. Reconstitute in sterile water to a concentration of 1.0 mg/mL. |
| Stability and Storage | The lyophilized antibody is stable for at least 5 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
| Preparation | Monoclonal antibodies were produced in mice using recombinant human IL-11 as the immunizing antigen. Monoclonal antibody was purified from ascites fluid by Protein A affinity chromatography. |
| Antigen | Recombinant human IL-11 |
| Application | ELISA |
| Synonyms | IL11, Adipogenesis Inhibitory Factor, AGIF, IL-11 |
| Uniprot ID | P20809 |
| Protein RefSeq | NP_000632.1 |
| mRNA RefSeq | NM_000641 |