Description / anti-mouse IL-1 beta monoclonal antibody
IL-1 is a name that designates two proteins, IL-1 alpha and IL-1 beta, that are the products of distinct genes, but recognize the same cell surface receptors. IL-1 alpha and IL-1 beta are structurally related polypeptides that show approximately 25% homology at the amino acid level. Both proteins are produced by a wide variety of cells in response to stimuli such as those produced by inflammatory agents, infections, or microbial endotoxins.
More Information
| Size | 50 µg |
|---|---|
| Source | Rat |
| Isotype | IgG2 |
| Biological Activity | Western Blot: 1:100-500 |
| Clone Nr. | (#11N21) |
| Species Reactivity | Mouse, further cross-reactivities have not been tested yet. |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with mouse recombinant protein of IL-1b. |
| Antigen | recombinant mouse IL-1beta |
| Application | WB |
| Synonyms | interleukin 1 beta |
| Uniprot ID | P10749 |
| Protein RefSeq | NP_032387 |
| mRNA RefSeq | NM_008361 |