Description / human IFN omega protein
IFN-ω is a type I interferon, which can be induced by virus-infected leukocytes. Members of the type I interferon family, which includes IFN-alpha, IFN-ß, and IFN-ω, signal through IFNAR-1/IFNAR-2 receptor complex, and exert antiviral and antiproliferative activities. IFN-ω exhibits about 75% sequence homology with IFN-alpha, and contains two conserved disulfide bonds, which are necessary for full biological activity. Recombinant Human IFN-ω is a 19.9 kDa protein consisting of 172 amino acid residues.
More Information
| Size | 20 µg |
|---|---|
| Source | E. coli |
| Biological Activity | The ED50 was determined by a cytotoxicity assay using Human TF-1 cells is ≤ 0.01 ng/ml, corresponding to a specific activity of ≥ 1 x 108 units/mg. |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 172 |
| Molecular Weight | 19.9 kDa |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Protein Sequence | CDLPQNHGLL SRNTLVLLHQ MRRISPFLCL KDRRDFRFPQ EMVKGSQLQK AHVMSVLHEM LQQIFSLFHT ERSSAAWNMT LLDQLHTGLH QQLQHLETCL LQVVGEGESA GAISSPALTL RRYFQGIRVY LKEKKYSDCA WEVVRMEIMK SLFLSTNMQE RLRSKDRDLG SS |
| Synonyms | IFNW1; Interferon omega |
| Uniprot ID | P05000 |
| Protein RefSeq | NP_002168.1 |
| mRNA RefSeq | NM_002177 |