anti-mouse IFN gamma polyclonal antibody Anti-Mouse 100 µg
Description / anti-mouse IFN gamma polyclonal antibody
IFN gamma (IFN-γ) is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signalling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signalling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulates the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils.
More Information
| Size | 100 µg |
|---|---|
| Source | Rabbit |
| Clone Nr. | Rabbit IgG |
| Species Reactivity | Mouse |
| Formulation | lyophilized from PBS |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
| Preparation | Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant murine IFN-gamma (murine Interferon-gamma). Anti-murine IFN-gamma specific antibody was purified by affinity chromatography employing immobilized murine IFN-gamma matrix. |
| Antigen | Recombinant mouse IFN-gamma |
| Application | ELISA, WB, N |
| Synonyms | Ifng; Ifg; IFN-g |
| Uniprot ID | P01580 |
| Protein RefSeq | NP_032363 |
| mRNA RefSeq | NM_008337 |