Description / anti-mouse Hedgehog interacting Protein (HIP) monoclonal antibody
Hedgehog-interacting protein )HIP) or Reg3B (regenerating islet-derived protein III beta; also PAPI) is a secreted, 17 kDa member of the Reg gene family, C-type lectin gene superfamily. It is found in pancreatic acinar cells, intestinal enterocytes and developing spinal motoneurons. Reg3B may play a role in intestinal epithelial cell renewal. It contains one C-type lectin domain. Mature mouse Reg3B is 91% and 67% aa identical to rat and human Reg3B, respectively.
More Information
| Size | 100 µg |
|---|---|
| Source | Rat |
| Isotype | IgG2 |
| Clone Nr. | (#8L46) |
| Species Reactivity | Mouse |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant protein of HIP extracellular domain. The IgG2 fraction of the culture supernatant was purified by Protein A/G affinity |
| Antigen | recombinant mouse protein of Hip EC-domain |
| Application | WB |
| Synonyms | hhip; hip; Xhip |
| Uniprot ID | Q7TN16 |
| Protein RefSeq | NP_064655.4 |
| mRNA RefSeq | NM_020259.4 |