Description / FGFR-2
Fibroblast Growth Factor Receptor 2 (FGF R2) is one of four closely related transmembrane tyrosine kinases (FGF R1-4) that function as receptors for the fibroblast growth factor family. Multiple isoforms are generated by alternative mRNA splicing resulting in extracellular domains with three (α isoforms) or two (β isoforms) Ig-like domains. In addition, alternative exon usage in the Ig III (membrane proximal) domain results in IIIb or IIIc isoforms.
More Information
| Size | 100 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG1 |
| Clone Nr. | (#6L19) |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | The antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with the recombinant extracellular domain of human Fibroblast Growth Factor Receptor-2 (sFGFR-2). The IgG1 fraction of the tissue culture supernatant |
| Antigen | Recombinant human FGF-R2 EC domain |
| Application | WB, IHC (P), N |
| Synonyms | FGFR2; BEK; JWS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM |
| Uniprot ID | P21802 |
| Protein RefSeq | NP_000132 |
| mRNA RefSeq | NM_000141 |