FGF acidic Mouse 50 µg

In stock

Cat-Nr.
M10-045
Size
50 µg
  €221.00

Description / FGF acidic

FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant mouse FGF-acidic is a 15.9 kDa protein consisting of 141 amino acid residues.

More Information

Size 50 µg
Source E. coli
Biological Activity Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by 3T3 cells in the presence of heparin is ≤ 0.5 ng/ml (≥ 2 x 106 units/mg). Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤
Purity Confirmation > 98% by SDS-PAGE & HPLC analyses
Length [aa] 141
Molecular Weight 15.9 kDa
Species Reactivity Mouse
Formulation lyophilized
Protein Sequence MFNLPLGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SAGEVYIKGT ETGQYLAMDT EGLLYGSQTP NEECLFLERL EENHYNTYTS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D
Synonyms HBGF-1; aFGF; acidic fibroblast growth factor; fibroblast growth factor 1 (acidic); heparin-binding growth factor 1
Uniprot ID P61148
Protein RefSeq NP_034327.1
mRNA RefSeq NM_010197.3

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